Unlimited Practice Guide · PTCE · ptce.md

High-alert medications (ISMP)

ptce/safety/high-alert · integrity: practice_only

Claim

High-alert medications bear a heightened risk of causing significant patient harm when used in error. ISMP publishes setting-specific high-alert lists (e.g., acute care) that include classes such as anticoagulants, insulin, opioids, and neuromuscular blocking agents — used to drive extra safeguards, not to ban the drugs.

Plain

High-alert ≠ “never use.” It means extra checks (independent double-check, smart pumps, limited access). Know the ISMP class examples.

Citations

  1. ISMP List of High-Alert Medications in Acute Care Settings (2024) (ISMP High-Alert Acute Care List Jan 2024) — source
    Classes/Categories of Medications … antithrombotic agents … insulin, subcutaneous and IV … neuromuscular blocking agents … opioids, all routes of administration
    retrieved 2026-09-07