{
  "schema": "upg.factor.v1",
  "exam": [
    "PTCE"
  ],
  "domain": "Federal Requirements",
  "confidence": 0.97,
  "updated_at": "2026-09-07",
  "token_cost_hint": 220,
  "integrity": "practice_only",
  "id": "ptce/federal/dea-schedules",
  "title": "Controlled substance schedules I\u2013V (federal)",
  "claim": "Federal law places controlled substances into five schedules (I\u2013V) based on accepted medical use, abuse potential, and dependence liability. Schedule I has no currently accepted medical use in treatment in the U.S.; Schedules II\u2013V have accepted medical use with decreasing relative abuse/dependence risk down the ladder.",
  "plain": "I = no accepted medical use (federal). II\u2013V = medical use allowed, controls get looser as the number rises. Exact drug lists live in 21 CFR 1308.",
  "citations": [
    {
      "authority": "21 U.S.C. \u00a7 812(b)",
      "url": "https://www.law.cornell.edu/uscode/text/21/812",
      "pin": "812(b)(1) Schedule I criteria",
      "retrieved_at": "2026-09-07",
      "quote": "Schedule I.\u2014 (A) The drug or other substance has a high potential for abuse. (B) The drug or other substance has no currently accepted medical use in treatment in the United States. (C) There is a lack of accepted safety for use of the drug or other substance under medical supervision."
    },
    {
      "authority": "21 CFR 1308.01",
      "url": "https://www.ecfr.gov/current/title-21/chapter-II/part-1308/section-1308.01",
      "pin": "1308.01",
      "retrieved_at": "2026-09-07",
      "quote": "Schedules of controlled substances established by section 202 of the Act (21 U.S.C. 812) \u2026 as they are changed, updated, and republished from time to time, are set forth in this part."
    }
  ],
  "html": "/factors/ptce/federal/dea-schedules",
  "json": "/factors/ptce/federal/dea-schedules.json"
}
