{
  "schema": "upg.factor.v1",
  "exam": [
    "PTCE"
  ],
  "domain": "Federal Requirements",
  "confidence": 0.98,
  "updated_at": "2026-09-07",
  "token_cost_hint": 220,
  "integrity": "practice_only",
  "id": "ptce/federal/dea-222",
  "title": "DEA Form 222 / electronic order \u2014 Schedule I\u2013II",
  "claim": "A DEA Form 222 or its DEA-compliant electronic equivalent is required for each distribution of a Schedule I or II controlled substance, with listed exceptions (e.g., certain exports, analytical lab deliveries, central-fill to retail).",
  "plain": "Ordering C-I/C-II from a supplier: Form 222 or CSOS electronic order. Techs may execute only under a valid power of attorney when the registrant authorizes it.",
  "citations": [
    {
      "authority": "21 CFR 1305.03",
      "url": "https://www.ecfr.gov/current/title-21/chapter-II/part-1305/section-1305.03",
      "pin": "1305.03",
      "retrieved_at": "2026-09-07",
      "quote": "Either a DEA Form 222 or its electronic equivalent as set forth in subpart C of this part and Part 1311 of this chapter is required for each distribution of a Schedule I or II controlled substance except for the following:"
    }
  ],
  "html": "/factors/ptce/federal/dea-222",
  "json": "/factors/ptce/federal/dea-222.json"
}